Article
Species-level assessment of the molecular basis of fluoroquinolone resistance among viridans group streptococci causing bacteraemia in cancer patients.
International journal of antimicrobial agents - 1 Jun 2014
Sahasrabhojane Pranoti, Galloway-Peña Jessica, Velazquez Luis, Saldaña Miguel, Horstmann Nicola, Tarrand Jeffrey, Shelburne Samuel A
Abstract excerpt
Viridans group streptococci (VGS) are a major cause of bacteraemia in neutropenic cancer patients, particularly those receiving fluoroquinolone prophylaxis. In this study, we sought to understand the molecular basis for fluoroquinolone resistance in VGS causing bacteraemia in cancer patients by a...
Topics
- Anti-Bacterial Agents
- Bacteremia
- Drug Resistance, Bacterial
- Fluoroquinolones
- Genes, Bacterial
- Genotype
- Humans
- Microbial Sensitivity Tests
- Molecular Typing
- Neoplasms
- Polymorphism, Genetic
- Sequence Analysis, DNA
- Streptococcal Infections
- Streptococcus