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Article

Dynamics of KRas on endosomes: involvement of acidic phospholipids in its association.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2014

Gelabert-Baldrich Mariona, Soriano-Castell David, Calvo Maria, Lu Albert, Viña-Vilaseca Arnau, Rentero Carles, Pol Albert, Grinstein Sergio, Enrich Carlos, Tebar Francesc

Abstract excerpt

The endocytic compartment is emerging as a functional platform for controlling important cellular processes. We have found that ∼10 to 15% of total KRas, a protein that is frequently mutated in cancer, is present on endosomes, independent of its activation state. The dynamics of GFP-KRas wild-typ...

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Identifiers

PMID: 24719356
DOI: 10.1096/fj.13-241158

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24719356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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