Article
VEGF-A blockade reduces reperfusion edema but favors arterial thromboembolism in a rat model of orthotopic lung transplantation.
Transplantation - 15 May 2014
Paulus Patrick, Holfeld Johannes, Scheller Bertram, Zacharowski Kai, Reissig Christin, Tybl Elisabeth, Ockelmann Pia Alexandra, Urbschat Anja
Abstract excerpt
BACKGROUND: Ischemia-reperfusion edema is a common early complication after lung transplantation where the hypoxia-induced vascular endothelial growth factor (VEGF)-A plays a pivotal role. It remains unclear whether a VEGF blockade is beneficial in lung transplantation. METHODS: VEGF-A blockade w...
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