Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iron dysregulation in Huntington's disease.

Journal of neurochemistry - 1 Aug 2014

Muller Michelle, Leavitt Blair R

Abstract excerpt

Huntington's disease (HD) is one of many neurodegenerative diseases with reported alterations in brain iron homeostasis that may contribute to neuropathogenesis. Iron accumulation in the specific brain areas of neurodegeneration in HD has been proposed based on observations in post-mortem tissue and magnetic resonance imaging studies. Altered magnetic resonance imaging signal within specific brain regions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Brain Chemistry
Share to Brain Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Huntingtin Protein

Share to Huntington Disease

Share to Nerve Tissue Proteins

Share to Nuclear Proteins

Source

Identifiers

PMID: 24717009
DOI: 10.1111/jnc.12739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iron dysregulation in Huntington's disease.PMID 24717009Read ↗

Brain Iron Metabolism and Neurodegenerative DisordersSemantic proximity Read ↗

Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington’s diseaseSemantic proximity Read ↗

Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease.Semantic proximity Read ↗

Neurodegeneration with brain iron accumulation.Semantic proximity Read ↗

The roles of iron and HFE genotype in neurological diseases.Semantic proximity Read ↗

The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A ViewpointSemantic proximity Read ↗

Iron dysregulation and neurodegeneration: the molecular connection.Semantic proximity Read ↗

Neurodegeneration with Brain Iron Accumulation Disorders: Valuable Models Aimed at Understanding the Pathogenesis of Iron DepositionSemantic proximity Read ↗

Neurodegenerations with Brain Iron Accumulation.Semantic proximity Read ↗

Update on neurodegeneration with brain iron accumulation.Semantic proximity Read ↗

HFE Mutations in Neurodegenerative Disease as a Model of Hormesis.Semantic proximity Read ↗

Iron, brain ageing and neurodegenerative disordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.