Article
Lack of any association of the CTLA-4 +49 G/A polymorphism with breast cancer risk in a North Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Minhas Sachin, Bhalla Sunita, Shokeen Yogender, Jauhri Mayank, Saxena Renu, Verma Ishwar Chandra, Aggarwal Shyam
Abstract excerpt
Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is an important protein involved in the regulation of the immune system. The +49 G/A polymorphism is the only genetic variation in the CTLA-4 gene that causes an amino acid change in the resulting protein. It is therefore the most extensively studied polymorphism among all CTLA-4 genetic variants and contributions to increasing the likelihood of developing cancer are well...
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