Article
Association between circadian genes, bipolar disorders and chronotypes.
Chronobiology international - 1 Aug 2014
Etain B, Jamain S, Milhiet V, Lajnef M, Boudebesse C, Dumaine A, Mathieu F, Gombert A, Ledudal K, Gard S, Kahn J P, Henry C, Boland A, Zelenika D, Lechner D, Lathrop M, Leboyer M, Bellivier F
Abstract excerpt
Abnormalities in circadian rhythms play an important role in the pathogenesis of bipolar disorders (BD). Previous genetic studies have reported discrepant results regarding associations between circadian genes and susceptibility to BD. Furthermore, plausible behavioral consequences of at-risk variants remain unclear since there is a paucity of correlates with phenotypic biomarkers such as chronotypes. Here, we...
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