Article
Identification of circadian gene variants in bipolar disorder in Latino populations.
Journal of affective disorders - 1 Nov 2015
Gonzalez Robert, Gonzalez Suzanne, Villa Erika, Ramirez Mercedes, Zavala Juan, Armas Regina, Contreras Javier, Dassori Albana, Leach Robin J, Flores Deborah, Jerez Alvaro, Raventós Henriette, Ontiveros Alfonso, Nicolini Humberto, Escamilla Michael
Abstract excerpt
BACKGROUND: Variations in circadian genes can impact biological rhythms. Given the rhythm disturbances that characterize bipolar disorder (BD), genes encoding components of molecular clocks are good candidate genes for the illness. METHODS: A family based association analysis of circadian gene single nucleotide polymorphisms (SNPs) and BD was conducted in Latino pedigrees. 884 individuals from 207 pedigrees...
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