Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord.

Development (Cambridge, England) - 1 Apr 2014

Duval Nathalie, Daubas Philippe, Bourcier de Carbon Céline, St Cloment Cécile, Tinevez Jean-Yves, Lopes Miguel, Ribes Vanessa, Robert Benot

Abstract excerpt

Dorsal spinal neurogenesis is orchestrated by the combined action of signals secreted from the roof plate organizer and a downstream transcriptional cascade. Within this cascade, Msx1 and Msx2, two homeodomain transcription factors (TFs), are induced earlier than bHLH neuralizing TFs. Whereas bHLH TFs have been shown to specify neuronal cell fate, the function of Msx genes remains poorly defined. We describe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Bone Morphogenetic Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Enhancer Elements, Genetic

Share to Interneurons

Share to MSX1 Transcription Factor

Share to Spinal Cord

Share to Stem Cells

Source

Identifiers

PMID: 24715462
DOI: 10.1242/dev.099002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord.PMID 24715462Read ↗

The role of the msh homeobox gene during Drosophila neurogenesis: implication for the dorsoventral specification of the neuroectoderm.Semantic proximity Read ↗

Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development.Semantic proximity Read ↗

Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity.Semantic proximity Read ↗

Regulation of axial elongation by Cdx.Semantic proximity Read ↗

dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development.Semantic proximity Read ↗

Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expressionSemantic proximity Read ↗

Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain.Semantic proximity Read ↗

Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract.Semantic proximity Read ↗

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.Semantic proximity Read ↗

Independent control of neurogenesis and dorsoventral patterning by NKX2-2Semantic proximity Read ↗

Expression and function of the columnar patterning gene msh in late embryonic brain development of Drosophila.Semantic proximity Read ↗

The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.