Divergence in the spatial pattern of gene expression between human duplicate genes.

doi:10.1101/gr.1133803

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Article

Divergence in the spatial pattern of gene expression between human duplicate genes.

Genome research - 1 Jul 2003

Makova Kateryna D, Li Wen-Hsiung

Abstract excerpt

Microarray gene expression data provide a wealth of information for elucidating the mode and tempo of molecular evolution. In the present study,we analyze the spatial expression pattern of human duplicate gene pairs by using oligonucleotide microarray data,and study the relationship between coding sequence divergence and expression divergence. First,we find a strong positive correlation between the proportion of...

Topics

Computational Biology
Databases, Genetic
Gene Expression Profiling
Gene Expression Regulation
Genes, Duplicate
Genetic Variation
Humans
Oligonucleotide Array Sequence Analysis

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Identifiers

PMID: 12840042
DOI: 10.1101/gr.1133803
PMCID: PMC403737

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