Article
Molecular trajectories leading to the alternative fates of duplicate genes.
PloS one - 1 Jan 2012
Marotta Michael, Piontkivska Helen, Tanaka Hisashi
Abstract excerpt
Gene duplication generates extra gene copies in which mutations can accumulate without risking the function of pre-existing genes. Such mutations modify duplicates and contribute to evolutionary novelties. However, the vast majority of duplicates appear to be short-lived and experience duplicate silencing within a few million years. Little is known about the molecular mechanisms leading to these alternative...
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