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Article

Frequency of genetic and epigenetic alterations of p14ARF and p16INK4A in head and neck cancer in a Hungarian population.

Pathology oncology research : POR - 1 Oct 2014

Kis Andrea, Tatár Tímea Zsófia, Gáll Tamás, Boda Róbert, Tar Ildikó, Major Tamás, Redl Pál, Gergely Lajos, Szarka Krisztina

Abstract excerpt

Occurrence of genetic and epigenetic alterations affecting p14ARF and p16INK4A were investigated in tumour samples of 37 oral (OSCC) and 28 laryngeal squamous cell cancer (LSCC) patients, and compared to exfoliated buccal epithelial cells of 68 healthy controls. Presence of deletions and mutations/polymorphisms affecting exons were examined using sequencing. Methylation status of promoters was assessed by...

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PMID: 24710824
DOI: 10.1007/s12253-014-9775-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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