Article
Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic.
BMC genomics - 8 Apr 2014
Mendum Tom A, Schuenemann Verena J, Roffey Simon, Taylor G Michael, Wu Huihai, Singh Pushpendra, Tucker Katie, Hinds Jason, Cole Stewart T, Kierzek Andrzej M, Nieselt Kay, Krause Johannes, Stewart Graham R
Abstract excerpt
BACKGROUND: Leprosy has afflicted humankind throughout history leaving evidence in both early texts and the archaeological record. In Britain, leprosy was widespread throughout the Middle Ages until its gradual and unexplained decline between the 14th and 16th centuries. The nature of this ancient endemic leprosy and its relationship to modern strains is only partly understood. Modern leprosy strains are...
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