Article
Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital.
PloS one - 1 Jan 2013
Taylor G Michael, Tucker Katie, Butler Rachel, Pike Alistair W G, Lewis Jamie, Roffey Simon, Marter Philip, Lee Oona Y-C, Wu Houdini H T, Minnikin David E, Besra Gurdyal S, Singh Pushpendra, Cole Stewart T, Stewart Graham R
Abstract excerpt
Nine burials excavated from the Magdalen Hill Archaeological Research Project (MHARP) in Winchester, UK, showing skeletal signs of lepromatous leprosy (LL) have been studied using a multidisciplinary approach including osteological, geochemical and biomolecular techniques. DNA from Mycobacterium leprae was amplified from all nine skeletons but not from control skeletons devoid of indicative pathology. In several...
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