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Article

Cell penetrating peptides and cationic antibacterial peptides: two sides of the same coin.

The Journal of biological chemistry - 23 May 2014

Rodriguez Plaza Jonathan G, Morales-Nava Rosmarbel, Diener Christian, Schreiber Gabriele, Gonzalez Zyanya D, Lara Ortiz Maria Teresa, Ortega Blake Ivan, Pantoja Omar, Volkmer Rudolf, Klipp Edda, Herrmann Andreas, Del Rio Gabriel

Abstract excerpt

Cell penetrating peptides (CPP) and cationic antibacterial peptides (CAP) have similar physicochemical properties and yet it is not understood how such similar peptides display different activities. To address this question, we used Iztli peptide 1 (IP-1) because it has both CPP and CAP activities. Combining experimental and computational modeling of the internalization of IP-1, we show it is not internalized by...

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Identifiers

PMID: 24706763
DOI: 10.1074/jbc.M113.515023
PMCID: PMC4031501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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