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Article

Cataract-linked mutation R188H promotes βB2-crystallin aggregation and fibrillization during acid denaturation.

Biochemical and biophysical research communications - 2 May 2014

Xi Yi-Bo, Zhang Kai, Dai An-Bang, Ji Shang-Rong, Yao Ke, Yan Yong-Bin

Abstract excerpt

Cataract is characterized by the formation of light-scattering protein aggregates in the lens. β/γ-Crystallins are the predominant structural proteins in the cytosol of lens fiber cells, and more than fifty β/γ-crystallin mutations have been linked to autosomal dominant congenital cataract. Howev...

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Identifiers

PMID: 24704203
DOI: 10.1016/j.bbrc.2014.03.119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24704203-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Cataract-linked mutation R188H promotes βB2-crystallin aggregation and fibrillization during acid denaturation.PMID 24704203Read ↗

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