Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting Mitochondria for Neuroprotection in Parkinson's Disease

9 Jan 2012

Abstract excerpt

SIGNIFICANCE: Several genetic causes of familial Parkinson's disease (PD) have now been identified and include mutations of genes encoding mitochondrial proteins. Mitochondrial complex I toxins can induce dopaminergic cell death and produce a parkinsonian state. Importantly, defects of mitochondrial function have been identified in postmortem substantia nigra from pathologically proven cases of PD. RECENT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22229791
DOI: 10.1089/ars.2011.4419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting Mitochondria for Neuroprotection in Parkinson's DiseasePMID 22229791Read ↗

The Centrality of Mitochondria in the Pathogenesis and Treatment of Parkinson's DiseaseSemantic proximity Read ↗

Targeting Mitochondrial Impairment in Parkinson's Disease: Challenges and OpportunitiesSemantic proximity Read ↗

Mitochondrial Dysfunction in Parkinson's Disease: Pathogenesis and NeuroprotectionSemantic proximity Read ↗

Targeting Mitochondria as a Therapeutic Approach for Parkinson’s DiseaseSemantic proximity Read ↗

Mitochondrial therapies for Parkinson's diseaseSemantic proximity Read ↗

Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to TherapySemantic proximity Read ↗

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic PerspectivesSemantic proximity Read ↗

Cell Death Pathways in Parkinson's Disease: Role of MitochondriaSemantic proximity Read ↗

Targeting mitophagy in Parkinson's disease.Semantic proximity Read ↗

Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potentialSemantic proximity Read ↗

Mitophagy in Parkinson’s Disease: Pathogenic and Therapeutic ImplicationsSemantic proximity Read ↗

Mitochondrial dysfunction and possible treatments in Parkinson's disease—a reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.