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Article

Influence of UGT2B7, OPRM1 and ABCB1 gene polymorphisms on postoperative morphine consumption.

Basic & clinical pharmacology & toxicology - 1 Nov 2014

Bastami Salumeh, Gupta Anil, Zackrisson Anna-Lena, Ahlner Johan, Osman Abdimajid, Uppugunduri Srinivas

Abstract excerpt

Therapeutic modulation of pain with morphine and other opioids is associated with significant variation in both effects and adverse effects in individual patients. Many factors including gene polymorphisms have been shown to contribute to the interindividual variability in the response to opioids. The aim of this study was to investigate the significance of UGT2B7, OPRM1 and ABCB1 polymorphisms for...

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Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Hysterectomy

Share to Morphine

Share to Pain, Postoperative

Share to Receptors, Opioid, mu

Share to Regression Analysis

Source

Identifiers

PMID: 24703092
DOI: 10.1111/bcpt.12248

Genes

ABCB1
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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