Article
Genetic loci associated with atrial fibrillation: relation to left atrial structure in the Framingham Heart Study.
Journal of the American Heart Association - 2 Apr 2014
Magnani Jared W, Yin Xiaoyan, McManus David D, Chuang Michael L, Cheng Susan, Lubitz Steven A, Arora Garima, Manning Warren J, Ellinor Patrick T, Benjamin Emelia J
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) results in significant morbidity and mortality. Genome-wide association studies (GWAS) have identified genetic variants associated with AF. Whether genetic variants associated with AF are also associated with atrial structure, an intermediate phenotype for AF, has had limited investigation. We sought to investigate associations between single nucleotide polymorphisms (SNPs)...
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