Article
Deep learning of left atrial structure and function provides link to atrial fibrillation risk.
Nature communications - 21 May 2024
Pirruccello James P, Di Achille Paolo, Choi Seung Hoan, Rämö Joel T, Khurshid Shaan, Nekoui Mahan, Jurgens Sean J, Nauffal Victor, Kany Shinwan, Ng Kenney, Friedman Samuel F, Batra Puneet, Lunetta Kathryn L, Palotie Aarno, Philippakis Anthony A, Ho Jennifer E, Lubitz Steven A, Ellinor Patrick T
Abstract excerpt
Increased left atrial volume and decreased left atrial function have long been associated with atrial fibrillation. The availability of large-scale cardiac magnetic resonance imaging data paired with genetic data provides a unique opportunity to assess the genetic contributions to left atrial structure and function, and understand their relationship with risk for atrial fibrillation. Here, we use deep learning...
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