Article
Downregulation of HDAC1 is involved in the cardiomyocyte differentiation from mesenchymal stem cells in a myocardial microenvironment.
PloS one - 1 Jan 2014
Lu Dong-feng, Yao Yan, Su Zi-zhuo, Zeng Zhao-hua, Xing Xiao-wen, He Zhi-yu, Zhang Chunxiang
Abstract excerpt
Under myocardial microenvironment, bone marrow-derived mesenchymal stem cells (MSCs) can transdifferentiate into cardiomyocytes (CMs). However, the role of histone deacetylase 1 (HDAC1) in this directed differentiation process remains unclear. The current study is to determine the acetylation reg...
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