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Article

miR-1-mediated induction of cardiogenesis in mesenchymal stem cells via downregulation of Hes-1.

BioMed research international - 1 Jan 2013

Huang Feng, Tang Liang, Fang Zhen-fei, Hu Xin-qun, Pan Jia-yi, Zhou Sheng-hua

Abstract excerpt

MicroRNAs (miRNAs, miRs) have the potential to control stem cells fate decisions. The cardiac- and skeletal-muscle-specific miRNA, miR-1, can regulate embryonic stem cells differentiation to cardiac lineage by suppressing gene expression of alternative lineages. Accordingly, we hypothesized that overexpression of miR-1 may also promote cardiac gene expression in mesenchymal stem cells. Since Notch signaling could...

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Identifiers

PMID: 23509692
DOI: 10.1155/2013/216286
PMCID: PMC3591156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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