Article
Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro.
Experimental biology and medicine (Maywood, N.J.) - 1 Jul 2004
Xu Wenrong, Zhang Xiran, Qian Hui, Zhu Wei, Sun Xiaochun, Hu Jiabo, Zhou Hong, Chen Yongchang
Abstract excerpt
A method for isolating adult human bone marrow mesenchymal stem cells (MSCs) was established, and the ability of human MSCs to differentiate into cells with characteristics of cardiomyocytes in vitro was investigated. Selected MSC surface antigens were analyzed by flow cytometry. The MSCs at Passage 2 were treated with 5-azacytidine to investigate their differentiation into cardiomyocytes. Characteristics of the...
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