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Article

Dendritic cells treated with crude Plasmodium berghei extracts acquire immune-modulatory properties and suppress the development of autoimmune neuroinflammation.

Immunology - 1 Oct 2014

Thomé Rodolfo, Issayama Luidy K, Alves da Costa Thiago, Gangi Rosária D, Ferreira Isadora T, Rapôso Catarina, Lopes Stefanie C P, da Cruz Höfling Maria Alice, Costa Fábio T M, Verinaud Liana

Abstract excerpt

Dendritic cells (DCs) are professional antigen-presenting cells specifically targeted during Plasmodium infection. Upon infection, DCs show impaired antigen presentation and T-cell activation abilities. In this study, we aimed to evaluate whether cellular extracts obtained from Plasmodium berghei-infected erythrocytes (PbX) modulate DCs phenotypically and functionally and the potential therapeutic usage of...

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Identifiers

PMID: 24689455
DOI: 10.1111/imm.12298
PMCID: PMC4172133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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