Article
The vertebrate genome: isochores and evolution.
Molecular biology and evolution - 1 Jan 1993
Bernardi G
Abstract excerpt
Vertebrate genomes are mosaics of isochores--namely, of long (> 300 kb), compositionally homogeneous DNA segments that can be subdivided into a small number of families characterized by different GC levels. In the human genome (which is representative of a number of mammalian genomes, and, more broadly, of the genomes of warm-blooded vertebrates), the compositional range of isochores is 30%-60% GC, and five...
Topics
- Animals
- Base Composition
- Biological Evolution
- Body Temperature
- Chromosome Banding
- Codon
- Humans
- Models, Genetic
- Mutation
- Selection, Genetic
- Species Specificity
- Vertebrates
