Article
Genetic diversity in the interference selection limit.
PLoS genetics - 1 Mar 2014
Good Benjamin H, Walczak Aleksandra M, Neher Richard A, Desai Michael M
Abstract excerpt
Pervasive natural selection can strongly influence observed patterns of genetic variation, but these effects remain poorly understood when multiple selected variants segregate in nearby regions of the genome. Classical population genetics fails to account for interference between linked mutations, which grows increasingly severe as the density of selected polymorphisms increases. Here, we describe a simple limit...
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