Article
Gasdermin-B promotes invasion and metastasis in breast cancer cells.
PloS one - 1 Jan 2014
Hergueta-Redondo Marta, Sarrió David, Molina-Crespo Ángela, Megias Diego, Mota Alba, Rojo-Sebastian Alejandro, García-Sanz Pablo, Morales Saleta, Abril Sandra, Cano Amparo, Peinado Héctor, Moreno-Bueno Gema
Abstract excerpt
Gasdermin B (GSDMB) belongs to the Gasdermin protein family that comprises four members (GSDMA-D). Gasdermin B expression has been detected in some tumor types such as hepatocarcinomas, gastric and cervix cancers; and its over-expression has been related to tumor progression. At least four splicing isoforms of GSDMB have been identified, which may play differential roles in cancer. However, the implication of...
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