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Article

Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression.

Oncology reports - 1 Aug 2018

Canzoneri Romina, Rabassa Martín Enrique, Gurruchaga Agustina, Ferretti Valeria, Palma Sabina, Isla-Larrain Marina, Croce María Virginia, Lacunza Ezequiel, Abba Martín Carlos

Abstract excerpt

RHBDD2 is an intramembrane pseudoprotease member of the Rhomboid superfamily. Our previous studies in breast and colorectal cancer indicate an association between RHBDD2 overexpression and advanced tumor stages. Two alternative transcriptional variants have been described for RHBDD2, which would be encoding for different RHBDD2 protein isoforms. The expression of these RHBDD2 variants/isoforms and its association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29901166
DOI: 10.3892/or.2018.6489

Genes

RHBDD2

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