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A Pan-cancer Analysis of Molecular Characteristics and Oncogenic Role of Gasdermins

2021-09-09

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe gasdermins (GSDMs) family is proposed to be pore-forming effector proteins that cause cell membrane permeabilization and pyroptosis. Despite our increasing knowledge of GSDMD, GSDME and GSDMB, the biological functions and the regulation of GSDM expression and activation remain elusive for most GSDMs. In this study, we analyzed the molecular characteristics and oncogenic ro...

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Literature Corpus work
e800df19-c78a-50cf-8735-9cedaff8315b
DOI
10.21203/rs.3.rs-870727/v1
Open publication

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A Pan-cancer Analysis of Molecular Characteristics and Oncogenic Role of GasderminsDOI 10.21203/rs.3.rs-870727/v1
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