Article
Quality metrics for stem cell-derived cardiac myocytes.
Stem cell reports - 11 Mar 2014
Sheehy Sean P, Pasqualini Francesco, Grosberg Anna, Park Sung Jin, Aratyn-Schaus Yvonne, Parker Kevin Kit
Abstract excerpt
Advances in stem cell manufacturing methods have made it possible to produce stem cell-derived cardiac myocytes at industrial scales for in vitro muscle physiology research purposes. Although FDA-mandated quality assurance metrics address safety issues in the manufacture of stem cell-based products, no standardized guidelines currently exist for the evaluation of stem cell-derived myocyte functionality. As a...
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