Article
The genetic basis of mast cell activation disease - looking through a glass darkly.
Critical reviews in oncology/hematology - 1 Feb 2015
Molderings Gerhard J
Abstract excerpt
Within the last decade, and in particular since 2012, research has greatly extended our understanding of the molecular basis of systemic mast cell activation disease (MCAD). Initial studies demonstrated that somatic mutations in the tyrosine kinase KIT led to the establishment of a clonal mast cell population. Recent studies, in particular those involving next generation sequencing analyses of advanced systemic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.