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Article

Engineering pre-SUMO4 as efficient substrate of SENP2.

Protein engineering, design & selection : PEDS - 1 Apr 2014

Liu Yan, Kieslich Chris A, Morikis Dimitrios, Liao Jiayu

Abstract excerpt

SUMOylation, one of the most important protein post-translational modifications, plays critical roles in a variety of physiological and pathological processes. SENP (Sentrin/SUMO-specific protease), a family of SUMO-specific proteases, is responsible for the processing of pre-SUMO and removal of SUMO from conjugated substrates. SUMO4, the latest discovered member in the SUMO family, has been found as a type 1...

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Source

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Identifiers

PMID: 24671712
DOI: 10.1093/protein/gzu004
PMCID: PMC3966678

Genes

SUMO4
SENP2
SUMO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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