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Article

Ecto-5'-nucleotidase (CD73) regulates host inflammatory responses and exacerbates murine salmonellosis.

Scientific reports - 27 Mar 2014

Alam M Samiul, Kuo Jennifer L, Ernst Peter B, Derr-Castillo Victoria, Pereira Marion, Gaines Dennis, Costales Matthew, Bigley Elmer, Williams Kristina

Abstract excerpt

Food-borne Salmonella spp., are a major cause of hospitalization and death. Adenosine, an important immune regulator of inflammation, limits tissue damage during infection. CD39 (nucleoside triphosphate dephosphorylase) combined with ecto-5'-nucleotidase (CD73) metabolizes ATP to adenosine. We st...

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Identifiers

PMID: 24670982
DOI: 10.1038/srep04486
PMCID: PMC3967249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24670982-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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