Article
Quantifying the uncertainty in heritability.
Journal of human genetics - 1 May 2014
Furlotte Nicholas A, Heckerman David, Lippert Christoph
Abstract excerpt
The use of mixed models to determine narrow-sense heritability and related quantities such as SNP heritability has received much recent attention. Less attention has been paid to the inherent variability in these estimates. One approach for quantifying variability in estimates of heritability is a frequentist approach, in which heritability is estimated using maximum likelihood and its variance is quantified...
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