Article
Prevalent RNA recognition motif duplication in the human genome.
RNA (New York, N.Y.) - 1 May 2014
Tsai Yihsuan S, Gomez Shawn M, Wang Zefeng
Abstract excerpt
The sequence-specific recognition of RNA by proteins is mediated through various RNA binding domains, with the RNA recognition motif (RRM) being the most frequent and present in >50% of RNA-binding proteins (RBPs). Many RBPs contain multiple RRMs, and it is unclear how each RRM contributes to the binding specificity of the entire protein. We found that RRMs within the same RBP (i.e., sibling RRMs) tend to have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.