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Article

Retrograde axonal transport and motor neuron disease.

Journal of neurochemistry - 1 Jul 2008

Ström Anna-Lena, Gal Jozsef, Shi Ping, Kasarskis Edward J, Hayward Lawrence J, Zhu Haining

Abstract excerpt

Transport of material between extensive neuronal processes and the cell body is crucial for neuronal function and survival. Growing evidence shows that deficits in axonal transport contribute to the pathogenesis of multiple neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS)...

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Source

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Identifiers

PMID: 18384644
DOI: 10.1111/j.1471-4159.2008.05393.x
PMCID: PMC4477783

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18384644-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Retrograde axonal transport and motor neuron disease.PMID 18384644Read ↗

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Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.Semantic proximity Read ↗

Deficits in axonal transport precede ALS symptoms in vivo.Semantic proximity Read ↗

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