Article
NK Cell Development and Function in Patients with Fanconi Anemia.
Critical reviews in immunology - 1 Jan 2021
Hashemi Elaheh, Bjorgaard Stacey, Wang Dandan, Uyemura Bradley, Riese Matthew, Thakar Monica S, Malarkannan Subramaniam
Abstract excerpt
Fanconi anemia (FA) is an inherited disorder characterized by diverse congenital malformations, progressive pancytopenia, and predisposition to hematological malignancies and solid tumors. The role of the Fanconi anemia pathway in DNA repair mechanisms and genome instability is well studied. However, the consequences of inherited mutations in genes encoding the FA proteins and the acquired mutations due to...
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