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Article

Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases

1 Jan 2014

Abstract excerpt

The current therapeutic regimen to combat chronic hepatitis C is not optimal due to substantial side effects and the failure of a significant proportion of patients to achieve a sustained virological response. Recently developed direct-acting antivirals targeting hepatitis C virus (HCV) enzymes reportedly increase the virologic response to therapy but may lead to a selection of drug-resistant variants. Besides...

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PMID: 24659882
DOI: 10.3748/wjg.v20.i11.2913

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