Article
Molecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 1 Apr 2014
Gowland Peter, Gassner Christoph, Hustinx Hein, Stolz Martin, Gottschalk Jochen, Tissot Jean-Daniel, Thierbach Jutta, Maier Andreas, Sigurdardottir Sonja, Still Franziska, Fontana Stefano, Frey Beat M, Niederhauser Christoph
Abstract excerpt
This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe phenotype...
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