Article
Serological weak D phenotypes: a review and guidance for interpreting the RhD blood type using the RHD genotype.
British journal of haematology - 1 Oct 2017
Sandler S Gerald, Chen Leonard N, Flegel Willy A
Abstract excerpt
Approximately 0·2-1% of routine RhD blood typings result in a "serological weak D phenotype." For more than 50 years, serological weak D phenotypes have been managed by policies to protect RhD-negative women of child-bearing potential from exposure to weak D antigens. Typically, blood donors with a serological weak D phenotype have been managed as RhD-positive, in contrast to transfusion recipients and pregnant...
Topics
- Amino Acid Substitution
- Antigenic Variation
- Blood Grouping and Crossmatching
- Blood Transfusion
- Cost-Benefit Analysis
- Female
- Gene Expression
- Genotype
- Humans
- Isoantibodies
- Mutation
- Phenotype
- Practice Guidelines as Topic
- Pregnancy
- Prevalence
- Rh-Hr Blood-Group System
- Serologic Tests