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Article

Involvement of the BDNF gene in loneliness in adolescence: a report of opposite gene effects in boys and girls.

PloS one - 1 Jan 2014

Verhagen Maaike, van Roekel Eeske, Engels Rutger C M E

Abstract excerpt

Previous research has shown that loneliness has a heritable component and that genes within the serotonin-, dopamine-, and oxytocin systems are related to loneliness in adolescence. In the present study, the relation between the BDNF Val66Met polymorphism and loneliness in adolescent boys and girls was examined in a longitudinal study spanning five annual waves (N = 305). Latent growth curve modeling (LGCM) was...

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Identifiers

PMID: 24647525
DOI: 10.1371/journal.pone.0092768
PMCID: PMC3960275

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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