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Article

BDNF Val66Met polymorphism modulates the effect of loneliness on white matter microstructure in young adults.

Biological psychology - 1 Dec 2017

Meng Jie, Hao Lei, Wei Dongtao, Sun Jiangzhou, Li Yu, Qiu Jiang

Abstract excerpt

Loneliness is a common experience. Susceptibility to loneliness is a stable trait and is heritable. Previous studies have suggested that loneliness may impact regional gray matter density and brain activation to social stimuli, but its relation to white matter structure and how it may interact with genetic factors remains unclear. In this study, we investigated whether and how a common polymorphism (Val66Met) in...

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Anisotropy
Brain-Derived Neurotrophic Factor
Gene-Environment Interaction
Gray Matter
Healthy Volunteers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28988974
DOI: 10.1016/j.biopsycho.2017.10.002

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BDNF

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