Article
Quantitative assessment of the influence of PSMA6 variant (rs1048990) on coronary artery disease risk.
Molecular biology reports - 1 Feb 2013
Wang Hairong, Jiang Mei, Zhu Hua, Chen Qihong, Gong Peihua, Lin Jie, Lu Jide, Qiu Jianping
Abstract excerpt
The proteasome system is a proteolytic pathway that regulates the expression of genes involved in inflammation. Recently, an association of a functional sequence variation, -8C/G, in the human proteasome subunit a type 6 gene (PSMA6) with the susceptibility to coronary artery disease (CAD) was reported. After that, several validation studies have been conducted among various ethnic populations, but the results...
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