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Article

p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 2001

Ko J, Humbert S, Bronson R T, Takahashi S, Kulkarni A B, Li E, Tsai L H

Abstract excerpt

Cyclin-dependent kinase 5 (Cdk5) plays a pivotal role in brain development and neuronal migration. Cdk5 is abundant in postmitotic, terminally differentiated neurons. The ability of Cdk5 to phosphorylate substrates is dependent on activation by its neuronal-specific activators p35 and p39. There...

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Identifiers

PMID: 11517264
PMCID: PMC6763073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11517264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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