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Article

Butyric acid stimulates bone sialoprotein gene transcription.

Journal of oral science - 1 Jun 2010

Yang Li, Li Zhengyang, Li Xinyue, Wang Zhitao, Wang Shuang, Sasaki Yoko, Takai Hideki, Ogata Yorimasa

Abstract excerpt

Butyric acid (sodium butyrate; BA) is an extracellular metabolite secreted from periodontopathic bacteria present in subgingival plaque. BA induces apoptosis of T and B cells, and acts as a potent inhibitor of histone deacetylases. Bone sialoprotein (BSP) is thought to function in the initial mineralization of bone, and may be crucial for osteoblast differentiation, bone matrix mineralization and tumor...

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Source

Identifiers

PMID: 20587946
DOI: 10.2334/josnusd.52.231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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