Article
Entropic Biological Score: a cell cycle investigation for GRNs inference.
Gene - 15 May 2014
Lopes Fabrício M, Ray Shubhra Sankar, Hashimoto Ronaldo F, Cesar Roberto M
Abstract excerpt
Inference of gene regulatory networks (GRNs) is one of the most challenging research problems of Systems Biology. In this investigation, a new GRNs inference methodology, called Entropic Biological Score (EBS), which linearly combines the mean conditional entropy (MCE) from expression levels and a Biological Score (BS), obtained by integrating different biological data sources, is proposed. The EBS is validated...
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