Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of crkl correlates with poor prognosis and cell proliferation in non‐small cell lung cancer

29 Jun 2012

Abstract excerpt

Crk-Like (CRKL) is an adapter protein that has crucial roles in multiple biological processes, including cell proliferation, adhesion, and migration. Amplification of CRKL gene was found in non-small cell lung cancer (NSCLC). However, the expression pattern of CRKL protein and its clinical significance in human NSCLC have not been well characterized to date. In this study, expression of CRKL was evaluated in 131...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Genetic factors in colorectal cancer
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22753141
DOI: 10.1002/mc.21935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of crkl correlates with poor prognosis and cell proliferation in non‐small cell lung cancerPMID 22753141Read ↗

Crk and CrkL as Therapeutic Targets for Cancer TreatmentSemantic proximity Read ↗

Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers.Semantic proximity Read ↗

Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial–mesenchymal transition and colorectal cancer aggressivenessSemantic proximity Read ↗

Identification of CRKL as an oncogenic biomarker for prognosis and immunotherapy in melanoma, and its potential molecular mechanismSemantic proximity Read ↗

Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancersSemantic proximity Read ↗

CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cellSemantic proximity Read ↗

Models of Crk Adaptor Proteins in CancerSemantic proximity Read ↗

FGFRL1 affects chemoresistance of small‐cell lung cancer by modulating the PI3K/Akt pathway via ENO1Semantic proximity Read ↗

Research Advances in CKLF-like MARVEL Transmembrane Domain-containing Family in Non-small Cell Lung CancerSemantic proximity Read ↗

Overexpression of CARMA3 in Non-Small-Cell Lung Cancer Is Linked for Tumor ProgressionSemantic proximity Read ↗

RACK1 Promotes Non-small-cell Lung Cancer Tumorigenicity through Activating Sonic Hedgehog Signaling PathwaySemantic proximity Read ↗

Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.