Article
Matrix metalloproteinase-2 promoter and tissue inhibitor of metalloproteinase-2 gene polymorphisms in non-Hodgkin's lymphoma.
International journal of cancer - 1 Sept 2012
Diao Lan-Ping, Ma Hui, Wei Guang-Chuan, Li Tao, Liu Hai-Sheng, Liu Li-Hong, Wu Li-Li, Zhao Gui-Min, Gao Yu-Huan
Abstract excerpt
Single nucleotide polymorphisms in the promoter regions of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMP) genes are associated with an adverse outcome in some cancers. We examined three polymorphisms: -1306C/T and -735C/T in MMP-2 and -418G/C in the TIMP-2 gene, using chain reaction restriction fragment length polymorphism typing analysis in 575 patients with non-Hodgkin's...
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