Article
Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families.
Journal of lipid research - 1 May 2014
Kulkarni Hemant, Meikle Peter J, Mamtani Manju, Weir Jacquelyn M, Almeida Marcio, Diego Vincent, Peralta Juan Manuel, Barlow Christopher K, Bellis Claire, Dyer Thomas D, Almasy Laura, Mahaney Michael C, Comuzzie Anthony G, Göring Harald H H, Curran Joanne E, Blangero John
Abstract excerpt
Plasma lipidome is now increasingly recognized as a potentially important marker of chronic diseases, but the exact extent of its contribution to the interindividual phenotypic variability in family studies is unknown. Here, we used the rich data from the ongoing San Antonio Family Heart Study (SAFHS) and developed a novel statistical approach to quantify the independent and additive value of the plasma lipidome...
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