Article
Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study.
Atherosclerosis - 1 Apr 2008
Stirnadel Heide, Lin Xiwu, Ling Hua, Song Kijoung, Barter Philip, Kesäniemi Y Antero, Mahley Robert, McPherson Ruth, Waeber Gérard, Bersot Thomas, Cohen Jonathan, Grundy Scott, Mitchell Braxton, Mooser Vincent, Waterworth Dawn
Abstract excerpt
Atherogenic dyslipidemia, manifest by low HDL-cholesterol and high TG levels, is an important component of ATP-III defined metabolic syndrome. Here, we dissected the phenotypic and genetic architecture of these traits by assessing their relationships with other metabolically relevant measures, including plasma adipo-cytokines, highly sensitive C-reactive protein (hsCRP) and LDL particle size, in a large family...
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