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Genome-wide association study reveals shared and distinct genetic architecture of fatty acids and oxylipins in the Hispanic Community Health Study/Study of Latinos.

HGG advances - 9 Jan 2025

Downie Carolina G, Highland Heather M, Alotaibi Mona, Welch Barrett M, Howard Annie Green, Cheng Susan, Miller Nick, Jain Mohit, Kaplan Robert C, Lilly Adam G, Long Tao, Sofer Tamar, Thyagarajan Bharat, Yu Bing, North Kari E, Avery Christy L

Abstract excerpt

Bioactive fatty acid-derived oxylipin molecules play key roles mediating inflammation and oxidative stress. Circulating levels of fatty acids and oxylipins are influenced by environmental and genetic factors; characterizing the genetic architecture of bioactive lipids could yield new insights into underlying biology. We performed a genome-wide association study (GWAS) of 81 fatty acids and oxylipins in 11,584...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39644095
DOI: 10.1016/j.xhgg.2024.100390
PMCID: PMC11751521

Genes

MAF
CARS2
SLCO1B1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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